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Aspergillus flavus uricase Antibody
Rabbit Polyclonal
600-401-NG7
50 µg
Liquid (sterile filtered)
WB, ELISA
Rabbit
Shipping info:
$50.00 to US & $70.00 to Canada for most products. Final costs are calculated at checkout.
Product Details
Anti-Aspergillus flavus uricase (Rabbit) Antibody - 600-401-NG7
Rabbit Anti-Rasburicase Antibody, Rabbit Anti-Aspergillus flavus uricase Antibody
Rabbit
Polyclonal
IgG
Target Details
uaZ
Recombinant Protein
Recombinant Aspergillus flavus uricase
Rabbit Anti-Aspergillus flavus uricase Antibody has been affinity purified using sepharose resins with immobilized Aspergillus flavus uricase.
Application Details
ELISA, WB
Affinity purified rabbit polyclonal Anti-Aspergillus flavus uricase antibodies have been tested for use in Western Blot and ELISA. This antibody recognizes structured uricase and will work in western blot when the protein are either denatured or in its native form. Although not tested, this antibody being affinity-purified, polyclonal raised using whole A. flavus uricase immunized to rabbit could be useful in detection of uricases from Aspergillus spp that share sequence homologies more than 80%. Specific conditions for reactivity should be optimized by the end user.
Formulation
1.15 mg/mL by UV absorbance at 280 nm
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
None
None
Shipping & Handling
Wet Ice
Store vial at 2-8° C. Dilute only prior to immediate use.
Expiration date is six (6) months from date of receipt.
Aspergillus flavus uricase (Rasburicase) is currently used for the treatment of gout and hyperuricemia occurring in tumor lysis syndrome. Rasburicase, sold under the brand name Elitek in the US and Fasturtec in the EU, is a medication that helps to clear uric acid from the blood. It is a recombinant version of urate oxidase, an enzyme that metabolizes uric acid to allantoin. Urate oxidase is known to be present in many mammals but does not naturally occur in humans. The concentration of uric acid in human serum is 1.5–6.0 mg/dl for women and 2.5–7.0 mg/dl for men. Any increase in the catabolism of purines or decrease in uric acid excretion leads to build up of uric acid in the form of monosodium urate crystals in joints or soft tissues. Moreover, hyperuricemia is also observed tumor lysis syndrome (TLS) and is caused by massive tumor cell lysis followed by catabolism of the nucleic acids to uric acid after chemotherapeutic treatment.
This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.